Drostanolone Propionate by CYGNUS PHARMACEUTICAL: An Anabolic Androgenic Steroid

Drostanolone Propionate is an anabolic androgenic steroid that first appeared on the market around 1970 under the trade name Masteron, manufactured by Syntex.

Structural Composition and Derivation

Drostanolone Propionate is a dihydrotestosterone (DHT) derived anabolic steroid. Specifically, Masteron is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position. This modification protects the hormone from metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme found in skeletal muscle and significantly increases the hormone’s anabolic nature. The small/short Propionate ester is attached to control the hormone’s release time.

Functional Properties and Applications

Masteron is well-known for being one of the few anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This unique property makes it effective in treating breast cancer. In fact, the combination of Masteron and Tamoxifen Citrate has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders, as it could potentially eliminate the need for an anti-estrogen when used in the right cycle.

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